Recombinant Human ELOC protein, His & T7-tagged
| Cat.No. : | ELOC-1097H |
| Product Overview : | Recombinant Human ELOC aa. (Met1~Cys112 (Accession # Q15369) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
| Description : | This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His & T7 |
| Form : | Freeze-dried powder |
| Molecular Mass : | Predicted Molecular Mass: 16.2kDa. |
| Protein length : | Met1~Cys112 (Accession # Q15369) |
| Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
| Purity : | >95% |
| Characteristic : | The isoelectric point is 4.7. |
| Applications : | SDS-PAGE; WB; ELISA; IP. |
| Stability : | The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
| Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
| Storage buffer : | Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative. |
| Reconstitution : | Reconstitute in sterile ddH2O. |
| Gene Name : | ELOC elongin C [ Homo sapiens (human) ] |
| Official Symbol : | ELOC |
| Synonyms : | ELOC; elongin C; SIII; TCEB1; elongin-C; transcription elongation factor B polypeptide 1; RNA polymerase II transcription factor SIII subunit C; SIII p15; elongin 15 kDa subunit; transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); transcription elongation factor B subunit 1 |
| Gene ID : | 6921 |
| mRNA Refseq : | NM_001204857.1 |
| Protein Refseq : | NP_001191786.1 |
| UniProt ID : | Q15369 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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