Recombinant Human ENG protein, His-Avi-tagged

• Cat.No.: ENG-813H
• Product Overview: Recombinant Human endoglin Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains Glu26-Gly586.

Specification

• Description: Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells . Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 63.7 KDa. Due to glycosylation, the protein migrates to 70- 82KDa based on Bis-Tris PAGE result.
• Protein length: Glu26-Gly586
• Endotoxin: Less than 0.05EU per ug by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: ENG
• Official Symbol: ENG
• Synonyms: CD105 antigen; CD105; Endoglin; ENDOsler-Rendu-Weber syndrome 1; ENG; HHT1FLJ41744; ORW; ORW1
• Gene ID: 2022
• mRNA Refseq: NM_000118.2
• Protein Refseq: NP_000109.1
• MIM: 131195
• UniProt ID: P17813