| Cat.No. : |
ENPP1&ENPP2-3892H |
| Product Overview : |
Recombinant Human ENPP-2 (Asp49-Trp144, Accession # Q13822), ENPP-1 (Val191-Leu591, Accession # P22413) and ENPP-2 (Asn532-Ile863, Accession # Q13822) protein with a His tag at N-terminus was expressed in Mouse myeloma cell line. |
| Description : |
This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. |
| Source : |
NS0 |
| Species : |
Human |
| Tag : |
His |
| Bio-activity : |
Measured by its ability to hydrolyze thymidine 5'-monophosphate p-nitrophenyl ester. The specific activity is >35,000 pmol/min/μg, as measured under the described conditions. |
| Molecular Mass : |
96 kDa |
| Endotoxin : |
<1.0 EU per 1 μg of the protein by the LAL method. |
| Purity : |
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
| Storage : |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
3 months, -20 to -70 centigrade under sterile conditions after opening. |
| Storage Buffer : |
Supplied as a 0.2 μm filtered solution in Tris and NaCl. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.