Recombinant Human ENSA Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human ENSA Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : ENSA-1710H
Product Overview : ENSA MS Standard C13 and N15-labeled recombinant protein (NP_996925) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 15.1 kDa
AA Sequence : MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GDYKSLHWSV LLCADEMQKY FDSGDYNMAK AKMKNKQLPS AGPDKNLVTG DHIPTPQDLP QRKSSLVTSK LAGGQVETRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : ENSA endosulfine alpha [ Homo sapiens (human) ]
Official Symbol : ENSA
Synonyms : ENSA; endosulfine alpha; alpha-endosulfine; ARPP 19e; MGC4319; MGC8394; MGC78563; ARPP-19e;
Gene ID : 2029
mRNA Refseq : NM_207042
Protein Refseq : NP_996925
MIM : 603061
UniProt ID : O43768

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