| Description : |
Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1. Plays a role in the formation of cilia. Involved in cargo protein localization, such as PKD2, at primary cilia. Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
45.5 kDa |
| AA Sequence : |
MSGYQRHPGATPLSRARSLAIPDAP AFYERRSCLPQLNCERPHGRDLDSP FFGIRPAFMCYVPSPVLASVGDTDD RFEDLEEANPFSFREFLKTKNLGLS KEDPASRIYAKEASRHSLGLDHNSP PSQTGGYGLEYQQPFFEDPTGAGDL LDGEEDEDTGWSGAYLPSAIEQTHP ERVPAGTSPCSTYLSFFSTPSELAG PESLPSWALSDTDSRVSPASPAGSP SADFAVHGESLGDRHLRTLQISYDA LKDENSKLRRKLNEVQSFSEAQTEM VRTLERKLEAKMIKEESDYHDLESV VQQVEQNLELMTKRAVKAENHVVKL KQEISLLQAQVSNFQRENEALRCGQ GASLTVVKQNADVALQNLRVVMNSA QASIKQLVSGAETLNLVAEILKSID RISEIKDEEEDSTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
