Recombinant Human EPB49, His-tagged

• Cat.No.: EPB49-12480H
• Product Overview: Recombinant Human EPB49 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-405a.a.
• Description: Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: EPB49 erythrocyte membrane protein band 4.9 (dematin) [ Homo sapiens ]
• Official Symbol: EPB49
• Synonyms: EPB49; erythrocyte membrane protein band 4.9 (dematin); dematin; DMT; FLJ78462; FLJ98848
• Gene ID: 2039
• mRNA Refseq: NM_001114135
• Protein Refseq: NP_001107607
• MIM: 125305
• UniProt ID: Q08495
• Chromosome Location: 8p21.1
• Function: actin binding