Recombinant Human EPCAM protein, His-tagged EPCAM-72H

Recombinant Human EPCAM protein, His-tagged

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Recombinant Human EPCAM protein, His-tagged

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Cat.No. : EPCAM-72H
Product Overview : Recombinant human TACSTD1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description : TACSTD1, also known as tumor-associated calcium signal transducer 1, is a membrane glycoprotein expressed on adenomatous and simple epithelia, where it is involved in homophilic adhesion at the basolateral membrane. It may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation.
Source : Insect cell
Species : Human
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 28.2kDa (248aa)28-40kDa (SDS-PAGE under reducing conditions)
AA Sequence : QEECVCENYK LAVNCFVNNN RQCQCTSVGA QNTVICSKLA AKCLVMKAEM NGSKLGRRAK PEGALQNNDG LYDPDCDESG LFKAKQCNGTSTCWCVNTAG VRRTDKDTEI TCSERVRTYW IIIELKHKAR EKPYDSKSLR TALQKEITTR YQLDPKFITS ILYENNVITI DLVQNSSQKTQNDVDIADVA YYFEKDVKGE SLFHSKKMDL TVNGEQLDLD PGQTLIYYVD EKAPEFSMQG LKHHHHHH
Endotoxin : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity : >95% by SDS – PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1mg/ml (determined by Absorbance at 280nm)
Gene Name : EPCAM epithelial cell adhesion molecule [ Homo sapiens ]
Official Symbol : EPCAM
Synonyms : ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; epithelial glycoprotein 314; human epithelial glycoprotein-2; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); tumor-associated calcium signal transducer 1
Gene ID : 4072
mRNA Refseq : NM_002354
Protein Refseq : NP_002345
MIM : 185535
UniProt ID : P16422
Chromosome Location : 2p21
Function : cadherin binding involved in cell-cell adhesion; protein binding; protein complex binding

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