Recombinant Human EPH Receptor A6, GST-tagged

Cat.No. : EPHA6-1012H
Product Overview : Recombinant human EPHA6 (561-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
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Cat. No. : EPHA6-1012H
Description : EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases which have been implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in nervous systems. EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia. Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context.
Applications : Kinase Assay; Western Blot
Molecular Weight : 73 kDa
Expression System : Sf9 insect cells using baculovirus
Species : Human
Form : Recombinant protein stored in 50 mM Tris-HCl, ph 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
Specific Activity : 9.0 nmol/min/mg
Purity : > 70 %
Concentration : 0.1 ug/ul
Sequences : 561-end
Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways : Axon guidance; EPHA forward signaling; EphrinA-EPHA pathway
Gene Name : EPHA6 EPH receptor A6 [ Homo sapiens ]
Official Symbol : EPHA6
Synonyms : EPHA6; EPH receptor A6; UNQ6114; DKFZp434C1418; EPA6; FLJ35246; PRO57066; ephrin type-A receptor 6; EHK-2; OTTHUMP00000214353; ephrin receptor EphA6; OTTHUMP00000217916; OTTHUMP00000217917; EPH homology kinase 2; EC 2.7.10.1
Gene ID : 285220
mRNA Refseq : NM_001080448
Protein Refseq : NP_001073917
MIM : 600066
UniProt ID : B3KS12
Chromosome Location : 3q11.2
Function : ATP binding; ephrin receptor activity; molecular function; nucleotide binding; receptor activity

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