Description : |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
107.9 kDa |
AA Sequence : |
MERRWPLGLGLVLLLCAPLPPGAHA KEVTLMDTSKAQGELGWLLDPPKDG WSEQQQILNGTPLYMYQDCPMQGRR DTDHWLRSNWIYRGEEASRVHVELQ FTVRDCKSFPGGAGPLGCKETFNLL YMESDQDVGIQLRRPLFQKVTTVAA DQSFTIRDLASGSVKLNVERCSLGR LTRRGLYLAFHNPGACVALVSVRVF YQRCPETLNGLAQFPDTLPGPAGLV EVAGTCLPHARASPRPSGAPRMHCS PDGEWLVPVGRCHCEPGYEEGGSGE ACVACPSGSYRMDMDTPHCLTCPQQ STAESEGATICTCESGHYRAPGEGP QVACTGPPSAPRNLSFSASGTQLSL RWEPPADTGGRQDVRYSVRCSQCQG TAQDGGPCQPCGVGVHFSPGARGLT TPAVHVNGLEPYANYTFNVEAQNGV SGLGSSGHASTSVSISMGHAESLSG LSLRLVKKEPRQLELTWAGSRPRSP GANLTYELHVLNQDEERYQMVLEPR VLLTELQPDTTYIVRVRMLTPLGPG PFSPDHEFRTSPPVSRGLTGGEIVA VIFGLLLGAALLLGILVFRSRRAQR QRQQRQRDRATDVDREDKLWLKPYV DLQAYEDPAQGALDFTRELDPAWLM VDTVIGEGEFGEVYRGTLRLPSQDC KTVAIKTLKDTSPGGQWWNFLREAT IMGQFSHPHILHLEGVVTKRKPIMI ITEFMENGALDAFLREREDQLVPGQ LVAMLQGIASGMNYLSNHNYVHRDL AARNILVNQNLCCKVSDFGLTRLLD DFDGTYETQGGKIPIRWTAPEAIAH RIFTTASDVWSFGIVMWEVLSFGDK PYGEMSNQEVMKSIEDGYRLPPPVD CPAPLYELMKNCWAYDRARRPHFQK LQAHLEQLLANPHSLRTIANFDPRV TLRLPSLSGSDGIPYRTVSEWLESI RMKRYILHFHSAGLDTMECVLELTA EDLTQMGITLPGHQKRILCSIQGFK DTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |