Recombinant Human EPHA8 Protein, DDK/His-tagged

• Cat.No.: EPHA8-371H
• Product Overview: Recombinant Human EPHA8(Ala28-Thr542), transcript variant 1, fused with DDK/His tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&His
• Protein Length: Ala28-Thr542
• Description: This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
• Form: 1 x PBS, pH7.4, 10% glycerol.
• Molecular Mass: 60 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: EPHA8 EPH receptor A8 [ Homo sapiens ]
• Official Symbol: EPHA8
• Synonyms: EPHA8; EPH receptor A8; EEK, EphA8; ephrin type-A receptor 8; Hek3; EPH-like kinase 3; tyrosylprotein kinase; protein-tyrosine kinase; hydroxyaryl-protein kinase; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; tyrosine-protein kinase receptor EEK; EEK; EK3; HEK3; KIAA1459
• Gene ID: 2046
• mRNA Refseq: NM_020526
• Protein Refseq: NP_065387
• MIM: 176945
• UniProt ID: P29322