Recombinant Human ERBB3 Protein

• Cat.No.: ERBB3-197H
• Product Overview: Recombinant Human ERBB3 Protein(Ser20~Thr643) was expressed in HEK293 with five amino acids (DDDDK) at the C-terminus.

Specification

• Source: HEK293
• Species: Human
• Tag: N/A
• Protein length: Ser20~Thr643
• Form: Lyophilized from sterile PBS, pH7.4, 5% trehalose, 5% Mannitol.
• Bio-activity: Immobilized HER3/ERBB3 Protein, Human, Recombinant (ECD) at 2 μg/mL (100 μL/well) can bind NRG1 Beta 1 Protein, Human, Recombinant, Biotinylated (EGF Domain, Fc Tag), the EC50 is 122 ng/mL.
• Molecular Mass: The recombinant human ERBB3 consists 630 amino acids and predicts a molecular mass of 69.3 kDa.
• Endotoxin: <1.0EU per 1μg (determined by the LAL method)
• Purity: > 85 % as determined by SDS-PAGE.
• Storage: Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.415mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) [ Homo sapiens ]
• Official Symbol: ERBB3
• Synonyms: ERBB3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian); LCCS2, lethal congenital contracture syndrome 2; receptor tyrosine-protein kinase erbB-3; HER3; proto-oncogene-like protein c-ErbB-3; tyrosine kinase-type cell surface receptor HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; MGC88033
• Gene ID: 2065
• mRNA Refseq: NM_001005915
• Protein Refseq: NP_001005915
• MIM: 190151
• UniProt ID: P21860