Recombinant Human ERBB4 Protein, His-tagged
Cat.No. : | ERBB4-385H |
Product Overview : | Recombinant Human ERBB4(Cys29~Asn278) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 32.0kDa |
Protein length : | Cys29~Asn278 |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others |
Gene Name : | ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) [ Homo sapiens ] |
Official Symbol : | ERBB4 |
Synonyms : | ERBB4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v erb a avian erythroblastic leukemia viral oncogene homolog like 4; receptor tyrosine-protein kinase erbB-4; proto-oncogene-like protein c-ErbB-4; tyrosine kinase-type cell surface receptor HER4; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; HER4; p180erbB4; MGC138404; |
Gene ID : | 2066 |
mRNA Refseq : | NM_001042599 |
Protein Refseq : | NP_001036064 |
MIM : | 600543 |
UniProt ID : | Q15303 |
Products Types
◆ Recombinant Protein | ||
Erbb4-8720R | Active Recombinant Rat Erbb4 protein(Met1-Pro651), hFc-tagged | +Inquiry |
Erbb4-10551M | Recombinant Mouse Erbb4 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERBB4-240H | Recombinant Human ERBB4 Protein, Fc-tagged | +Inquiry |
Erbb4-971M | Recombinant Mouse Erbb4 Protein, MYC/DDK-tagged | +Inquiry |
ERBB4-69H | Recombinant Human ERBB4 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
ERBB4-001HCL | Recombinant Human ERBB4 cell lysate | +Inquiry |
ERBB4-895RCL | Recombinant Rat ERBB4 cell lysate | +Inquiry |
ERBB4-1417MCL | Recombinant Mouse ERBB4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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