| Description : |
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
127.9 kDa |
| AA Sequence : |
MYGSARSVGKVEPSSQSPGRSPRLP RSPRLGHRRTNSTGGSSGSSVGGGS GKTLSMENIQSLNAAYATSGPMYLS DHENVGSETPKSTMTLGRSGGRLPY GVRMTAMGSSPNIASSGVASDTIAF GEHHLPPVSMASTVPHSLRQARDNT IMDLQTQLKEVLRENDLLRKDVEVK ESKLSSSMNSIKTFWSPELKKERAL RKDEASKITIWKEQYRVVQEENQHM QMTIQALQDELRIQRDLNQLFQQDS SSRTGEPCVAELTEENFQRLHAEHE RQAKELFLLRKTLEEMELRIETQKQ TLNARDESIKKLLEMLQSKGLSAKA TEEDHERTRRLAEAEMHVHHLESLL EQKEKENSMLREEMHRRFENAPDSA KTKALQTVIEMKDSKISSMERGLRD LEEEIQMLKSNGALSTEEREEEMKQ MEVYRSHSKFMKNKVEQLKEELSSK EAQWEELKKKAAGLQAEIGQVKQEL SRKDTELLALQTKLETLTNQFSDSK QHIEVLKESLTAKEQRAAILQTEVD ALRLRLEEKETMLNKKTKQIQDMAE EKGTQAGEIHDLKDMLDVKERKVNV LQKKIENLQEQLRDKEKQMSSLKER VKSLQADTTNTDTALTTLEEALAEK ERTIERLKEQRDRDEREKQEEIDNY KKDLKDLKEKVSLLQGDLSEKEASL LDLKEHASSLASSGLKKDSRLKTLE IALEQKKEECLKMESQLKKAHEAAL EARASPEMSDRIQHLEREITRYKDE SSKAQAEVDRLLEILKEVENEKNDK DKKIAELERQVKDQNKKVANLKHKE QVEKKKSAQMLEEARRREDNLNDSS QQLQDSLRKKDDRIEELEEALRESV QITAEREMVLAQEESARTNAEKQVE ELLMAMEKVKQELESMKAKLSSTQQ SLAEKETHLTNLRAERRKHLEEVLE MKQEALLAAISEKDANIALLELSSS KKKTQEEVAALKREKDRLVQQLKQQ TQNRMKLMADNYEDDHFKSSHSNQT NHKPSPDQIIQPLLELDQNRSKLKL YIGHLTTLCHDRDPLILRGLTPPAS YNLDDDQAAWENELQKMTRGQLQDE LEKGERDNAELQEFANAILQQIADH CPDILEQVVNALEESSTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
