| Description : |
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
104.3 kDa |
| AA Sequence : |
MESGQPARRIAMAPLLEYERQLVLE LLDTDGLVVCARGLGADRLLYHFLQ LHCHPACLVLVLNTQPAEEEYFINQ LKIEGVEHLPRRVTNEITSNSRYEV YTQGGVIFATSRILVVDFLTDRIPS DLITGILVYRAHRIIESCQEAFILR LFRQKNKRGFIKAFTDNAVAFDTGF CHVERVMRNLFVRKLYLWPRFHVAV NSFLEQHKPEVVEIHVSMTPTMLAI QTAILDILNACLKELKCHNPSLEVE DLSLENAIGKPFDKTIRHYLDPLWH QLGAKTKSLVQDLKILRTLLQYLSQ YDCVTFLNLLESLRATEKAFGQNSG WLFLDSSTSMFINARARVYHLPDAK MSKKEKISEKMEIKEGEETKKELVL ESNPKWEALTEVLKEIEAENKESEA LGGPGQVLICASDDRTCSQLRDYIT LGAEAFLLRLYRKTFEKDSKAEEVW MKFRKEDSSKRIRKSHKRPKDPQNK ERASTKERTLKKKKRKLTLTQMVGK PEELEEEGDVEEGYRREISSSPESC PEEIKHEEFDVNLSSDAAFGILKEP LTIIHPLLGCSDPYALTRVLHEVEP RYVVLYDAELTFVRQLEIYRASRPG KPLRVYFLIYGGSTEEQRYLTALRK EKEAFEKLIREKASMVVPEEREGRD ETNLDLVRGTASADVSTDTRKAGGQ EQNGTQQSIVVDMREFRSELPSLIH RRGIDIEPVTLEVGDYILTPEMCVE RKSISDLIGSLNNGRLYSQCISMSR YYKRPVLLIEFDPSKPFSLTSRGAL FQEISSNDISSKLTLLTLHFPRLRI LWCPSPHATAELFEELKQSKPQPDA ATALAITADSETLPESEKYNPGPQD FLLKMPGVNAKNCRSLMHHVKNIAE LAALSQDELTSILGNAANAKQLYDF IHTSFAEVVSKGKGKKTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
