Recombinant Human ESRRA Protein, GST-tagged

• Cat.No.: ESRRA-3508H
• Product Overview: Human ESRRA full-length ORF ( NP_004442.3, 1 a.a. - 423 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 71.9 kDa
• AA Sequence: MSSQVVGIEPLYIKAEPASPDSPKG SSETETEPPVALAPGPAPTRCLPGH KEEEDGEGAGPGEQGGGKLVLSSLP KRLCLVCGDVASGYHYGVASCEACK AFFKRTIQGSIEYSCPASNECEITK RRRKACQACRFTKCLRVGMLKEGVR LDRVRGGRQKYKRRPEVDPLPFPGP FPAGPLAVAGGPRKTAAPVNALVSH LLVVEPEKLYAMPDPAGPDGHLPAV ATLCDLFDREIVVTISWAKSIPGFS SLSLSDQMSVLQSVWMEVLVLGVAQ RSLPLQDELAFAEDLVLDEEGARAA GLGELGAALLQLVRRLQALRLEREE YVLLKALALANSDSVHIEDAEAVEQ LREALHEALLEYEAGRAGPGGGAER RRAGRLLLTLPLLRQTAGKVLAHFY GVKLEGKVPMHKLFLEMLEAMMD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ESRRA estrogen-related receptor alpha [ Homo sapiens ]
• Official Symbol: ESRRA
• Synonyms: ESRRA; estrogen-related receptor alpha; ESRL1; steroid hormone receptor ERR1; ERR1; ERRa; ERRalpha; NR3B1; ERR-alpha; estrogen receptor-like 1; estrogen-related nuclear receptor alpha; nuclear receptor subfamily 3 group B member 1
• Gene ID: 2101
• mRNA Refseq: NM_004451
• Protein Refseq: NP_004442
• MIM: 601998
• UniProt ID: P11474