Recombinant Human ETF1 protein, MYC/DDK-tagged
Cat.No. : | ETF1-5893H |
Product Overview : | Recombinant Human ETF1 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
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Description : | This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 48.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | ETF1 eukaryotic translation termination factor 1 [ Homo sapiens ] |
Official Symbol : | ETF1 |
Synonyms : | ETF1; eukaryotic translation termination factor 1; ERF, ERF1, SUP45L1; eukaryotic peptide chain release factor subunit 1; eRF1; polypeptide chain release factor 1; RF1; sup45 (yeast omnipotent suppressor 45) homolog like 1; TB3 1; protein Cl1; eukaryotic release factor 1; sup45 (yeast omnipotent suppressor 45) homolog-like 1; ERF; ERF1; TB3-1; D5S1995; SUP45L1; MGC111066; |
Gene ID : | 2107 |
mRNA Refseq : | NM_004730 |
Protein Refseq : | NP_004721 |
MIM : | 600285 |
UniProt ID : | P62495 |
Chromosome Location : | 5q31.2 |
Pathway : | Eukaryotic Translation Termination, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Nonsense Mediated Decay Enhanced by the Exon Junction Complex, organism-specific biosystem; Nonsense Mediated Decay Independent of the Exon Junction Complex, organism-specific biosystem; Nonsense-Mediated Decay, organism-specific biosystem; Translation, organism-specific biosystem; |
Function : | RNA binding; protein binding; ribosome binding; translation release factor activity; translation release factor activity, codon specific; translation termination factor activity; |
Products Types
◆ Recombinant Protein | ||
ETF1-1333R | Recombinant Rhesus Macaque ETF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ETF1-3514H | Recombinant Human ETF1 Protein, GST-tagged | +Inquiry |
ETF1-1815R | Recombinant Rat ETF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Etf1-2878M | Recombinant Mouse Etf1 Protein, Myc/DDK-tagged | +Inquiry |
ETF1-12564H | Recombinant Human ETF1, GST-tagged | +Inquiry |
◆ Lysates | ||
ETF1-6533HCL | Recombinant Human ETF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThere may be clinical trials evaluating potential treatments or interventions for ETF1 protein disorders, and individuals and families affected by these disorders can consider participating in such trials.
Symptoms may include muscle weakness, lethargy, hypoglycemia, metabolic acidosis, and in some cases, developmental delays and neurological symptoms.
Yes, prenatal testing through genetic screening can detect mutations in the ETF1 gene, allowing for early intervention and management.
Diagnosis typically involves biochemical testing, genetic testing, and metabolic screening to identify abnormalities in fatty acid metabolism.
Yes, ETF1 protein disorders can affect individuals of all ages, from newborns to adults, and may present with different symptoms at different stages of life.
Customer Reviews (3)
Write a reviewWhat sets this protein apart is the outstanding technical support provided by the manufacturer.
Its versatility allows me to explore its diverse roles in various biochemical and biological processes accurately.
The ETF1 Protein is of exceptional quality and is precisely tailored to meet my experimental requirements.
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