Recombinant Human ETV6 Protein, GST-tagged

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Recombinant Human ETV6 Protein, GST-tagged

ETV6 Related Products

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Cat.No. : ETV6-3540H
Product Overview : Human ETV6 full-length ORF ( AAH43399, 1 a.a. - 452 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 75.46 kDa
AA Sequence : MSETPAQCSI KQERISYTPP ESPVPSYASS TPLHVPVPRA LRMEEDSIRL PAHLRLQPIY WSRDDVAQWL KWAENEFSLR PIDSNTFEMN GKALLLLTKE DFRYRSPHSG DVLYELLQHI LKQRKPRILF SPFFHPGNSI HTQPEVILHQ NHEEDNCVQR TPRPSVDNVH HNPPTIELLH RSRSPITTNH RPSPDPEQRP LRSPLDNMIR RLSPAERAQG PRPHQENNHQ ESYPLSVSPM ENNHCPASSE SHPKPSSPRQ ESTRVIQLMP SPIMHPLILN PRHSVDFKQS RLSEDGLHRE GKPINLSHRE DLAYMNHIMV SVSPPEEHAM PIGRIADCRL LWDYVYQLLS DSRYENFIRW EDKESKIFRI VDPNGLARLW GNHKNRTNMT YEKMSRALRH YYKLNIIRKE PGQRLLFRFM KTPDEIMSGR TDRLEHLESQ ELDEQIYQED EC
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : ETV6 ets variant 6 [ Homo sapiens ]
Official Symbol : ETV6
Synonyms : ETV6; ets variant 6; ets variant gene 6 (TEL oncogene); transcription factor ETV6; TEL; TEL oncogene; TEL1 oncogene; ETS-related protein Tel1; ETS translocation variant 6; TEL/ABL;
Gene ID : 2120
mRNA Refseq : NM_001987
Protein Refseq : NP_001978
MIM : 600618
UniProt ID : P41212

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