Recombinant Human EXO5 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | EXO5-6115H |
| Product Overview : | DEM1 MS Standard C13 and N15-labeled recombinant protein (NP_073611) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 41.9 kDa |
| AA Sequence : | MAETREEETV SAEASGFSDL SDSEFLEFLD LEDAQESKAL VNMPGPSSES LGKDDKPISL QNWKRGLDIL SPMERFHLKY LYVTDLATQN WCELQTAYGK ELPGFLAPEK AAVLDTGASI HLARELELHD LVTVPVTTKE DAWAIKFLNI LLLIPTLQSE GHIREFPVFG EVEGVLLVGV IDELHYTAKG ELELAELKTR RRPMLPLEAQ KKKDCFQVSL YKYIFDAMVQ GKVTPASLIH HTKLCLEKPL GPSVLRHAQQ GGFSVKSLGD LMELVFLSLT LSDLPVIDIL KIEYIHQETA TVLGTEIVAF KEKEVRAKVQ HYMAYWMGHR EPQGVDVEEA WKCRTCTYAD ICEWRKGSGV LSSTLAPQVK KAKTRTRPLE QKLISEEDLA ANDILDYKDD DDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | EXO5 exonuclease 5 [ Homo sapiens (human) ] |
| Official Symbol : | EXO5 |
| Synonyms : | EXO5; exonuclease 5; DEM1; Exo V; hExo5; C1orf176; exonuclease V; defects in morphology 1 homolog; defects in morphology protein 1 homolog; probable exonuclease V |
| Gene ID : | 64789 |
| mRNA Refseq : | NM_022774 |
| Protein Refseq : | NP_073611 |
| MIM : | 618601 |
| UniProt ID : | Q9H790 |
◆ Recombinant Protein
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| EXO5-1119H | Recombinant Human EXO5 Protein (1-373 aa), His-SUMO-tagged | +Inquiry |
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| EXO5-2295H | Recombinant Human EXO5 Protein, MYC/DDK-tagged | +Inquiry |
| EXO5-3531Z | Recombinant Zebrafish EXO5 | +Inquiry |
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