| Description : |
The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
80.5 kDa |
| AA Sequence : |
MIPPQEASARRREIEDKLKQEEETL SFIRDSLEKSDQLTKNMVSILSSFE SRLMKLENSIIPVHKQTENLQRLQE NVEKTLSCLDHVISYYHVASDTEKI IREGPTGRLEEYLGSMAKIQKAVEY FQDNSPDSPELNKVKLLFERGKEAL ESEFRSLMTRHSKVVSPVLILDLIS GDDDLEAQEDVTLEHLPESVLQDVI RISRWLVEYGRNQDFMNVYYQIRSS QLDRSIKGLKEHFHKSSSSSGVPYS PAIPNKRKDTPTKKPVKRPGTIRKA QNLLKQYSQHGLDGKKGGSNLIPLE GHEHDFRVKHLSEALNDKHGPLAGR DDMLDVETDAYIHCVSAFVKLAQSE YQLLADIIPEHHQKKTFDSLIQDAL DGLMLEGENIVSAARKAIVRHDFST VLTVFPILRHLKQTKPEFDQVLQGT AASTKNKLPGLITSMETIGAKALED FADNIKNDPDKEYNMPKDGTVHELT SNAILFLQQLLDFQETAGAMLASQE TSSSATSYSSEFSKRLLSTYICKVL GNLQLNLLSKSKVYEDPALSAIFLH NNYNYILKSLEKSELIQLVAVTQKT AERSYREHIEQQIQTYQRSWLKVTD YIAEKNLPVFQPGVKLRDKERQIIK ERFKGFNDGLEELCKIQKAWAIPDT EQRDRIRQAQKTIVKETYGAFLQKF GSVPFTKNPEKYIKYGVEQVGDMID RLFDTSATRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
