| Description : |
This gene encodes a component of the exocyst complex, an evolutionarily conserved multi-protein complex that plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. This protein is a target of activated Ral subfamily of GTPases and thereby regulates exocytosis by tethering vesicles to the plasma membrane. Mutations in this gene may be related to Joubert syndrome. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
81.6 kDa |
| AA Sequence : |
MAMAMSDSGASRLRRQLESGGFEAR LYVKQLSQQSDGDRDLQEHRQRIQA LAEETAQNLKRNVYQNYRQFIETAR EISYLESEMYQLSHLLTEQKSSLES IPLTLLPAAAAAGAAAASGGEEGVG GAGGRDHLRGQAGFFSTPGGASRDG SGPGEEGKQRTLTTLLEKVEGCRHL LETPGQYLVYNGDLVEYDADHMAQL QRVHGFLMNDCLLVATWLPQRRGMY RYNALYSLDGLAVVNVKDNPPMKDM FKLLMFPESRIFQAENAKIKREWLE VLEDTKRALSEKRRREQEEAAAPRG PPQVTSKATNPFEDDEEEEPAVPEV EEEKVDLSMEWIQELPEDLDVCIAQ RDFEGAVDLLDKLNHYLEDKPSPPP VKELRAKVEERVRQLTEVLVFELSP DRSLRGGPKATRRAVSQLIRLGQCT KACELFLRNRAAAVHTAIRQLRIEG ATLLYIHKLCHVFFTSLLETAREFE IDFAGTDSGCYSAFVVWARSAMGMF VDAFSKQVFDSKESLSTAAECVKVA KEHCQQLGDIGLDLTFIIHALLVKD IQGALHSYKEIIIEATKHRNSEEMW RRMNLMTPEALGKLKEEMKSCGVSN FEQYTGDDCWVNLSYTVVAFTKQTM GFLEEALKLYFPELHMVLLESLVEI ILVAVQHVDYSLRCEQDPEKKAFIR QNASFLYETVLPVVEKRFEEGVGKP AKQLQDLRNASRLIRVNPESTTSVV TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
