Recombinant Human EYA4 Protein, GST-tagged

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Recombinant Human EYA4 Protein, GST-tagged

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Cat.No. : EYA4-3595H
Product Overview : Human EYA4 full-length ORF ( NP_742101.2, 1 a.a. - 616 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 93.5 kDa
AA Sequence : MEDSQDLNEQ SVKKTCTESD VSQSQNSRSM EMQDLASPHT LVGGGDTPGS SKLEKSNLSS TSVTTNGTGV SLLAVKTEPL NSSETTATTG DGALDTFTGS VITSSGYSPR SAHQYSPQLY PSKPYPHILS TPAAQTMSAY AGQTQYSGMQ QPAVYTAYSQ TGQPYSLPTY DLGVMLPAIK TESGLSQTQS PLQSGCLSYS PGFSTPQPGQ TPYSYQMPGS SFAPSSTIYA NNSVSNSTNF SGSQQDYPSY TAFGQNQYAQ YYSASTYGAY MTSNNTADGT PSSTSTYQLQ ESLPGLTNQP GEFDTMQSPS TPIKDLDERT CRSSGSKSRG RGRKNNPSPP PDSDLERVFV WDLDETIIVF HSLLTGSYAQ KYGKDPPMAV TLGLRMEEMI FNLADTHLFF NDLEECDQVH IDDVSSDDNG QDLSTYSFAT DGFHAAASSA NLCLPTGVRG GVDWMRKLAF RYRRVKELYN TYKNNVGGLL GPAKRDAWLQ LRAEIEGLTD SWLTNALKSL SIISTRSNCI NVLVTTTQLI PALAKVLLYS LGGAFPIENI YSATKIGKES CFERIMQRFG RKVVYVVIGD GVEEEQAAKK HNMPFWRISS HSDLLALHQA LELEYL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : EYA4 eyes absent homolog 4 (Drosophila) [ Homo sapiens ]
Official Symbol : EYA4
Synonyms : EYA4; eyes absent homolog 4 (Drosophila); CMD1J, DFNA10, eyes absent (Drosophila) homolog 4; eyes absent homolog 4; dJ78N10.1 (eyes absent); CMD1J; DFNA10;
Gene ID : 2070
mRNA Refseq : NM_004100
Protein Refseq : NP_004091
MIM : 603550
UniProt ID : O95677

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