Species : |
Human |
Source : |
HEK293 |
Tag : |
DDK&Myc |
Description : |
This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia. |
Molecular Mass : |
42.6 kDa |
Purity : |
>80% as determined by SDS-PAGE and Coomassie blue staining |
Storage buffer : |
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Concentration : |
>50 ug/mL as determined by microplate BCA method |
Preparation : |
Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage : |
Store at -800C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
OfficialSymbol : |
FA2H |