Recombinant Human, FABP3 His-tagged

• Cat.No.: FABP3-3678H
• Product Overview: Total 142 AA. MW: 15.97 kDa (calculated). N-Terminal His-tag, 10 extra AA (highlighted).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer.
• Form: Filtered (0,4 μm) and lyophilized in 0.5 mg/mL in 20mM TRIS, 50mM NaCl, pH 7.5
• Research topic: Energy metabolism and body weight regulation
• Reconstitution: Add deionized water to prepare a working stock solution of 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
• Applications: Western blotting
• Quality Control Test: BCA to determine quantity of the protein; SDS PAGE to determine purity of the protein
• Sequences of amino acids: MKHHHHHHAS VDAFLGTWKL VDSKNFDDYM KSLGVGFATR QVASMTKPTT IIEKNGDILT LKTHSTFKNT EISFKLGVEF DETTADDRKV KSIVTLDGGK LVHLQKWDGQ ETTLVRELID GKLILTLTHG TAVCTRTYEK EA
• Storage: Store lyophilized protein at -80°C. Lyophilized protein remains stable until the expiry date when stored at -80°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for one week.

Gene Information

• Gene Name: FABP3 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) [ Homo sapiens ]
• Official Symbol: FABP3
• Synonyms: FABP3; fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor); MDGI; FABP11; H-FABP; O-FABP; fatty acid binding protein 3; fatty acid binding protein 11; mammary-derived growth inhibitor; Fatty acid-binding protein 3, muscle; Fatty acid-binding protein, heart; M-FABP; Muscle fatty acid-binding protein; Mammary-derived growth inhibitor; OTTHUMP00000003898
• Gene ID: 2170
• mRNA Refseq: NM_004102
• Protein Refseq: NP_004093
• MIM: 134651
• UniProt ID: P05413
• Chromosome Location: 1p33-p32
• Pathway: PPAR signaling pathway
• Function: fatty acid binding; icosatetraenoic acid binding; long-chain fatty acid transporter activity; transporter activity