Recombinant Human FADS2 Protein, GST-tagged

• Cat.No.: FADS2-3643H
• Product Overview: Human FADS2 full-length ORF ( NP_004256.1, 1 a.a. - 444 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 78.7 kDa
• AA Sequence: MGKGGNQGEGAAEREVSVPTFSWEE IQKHNLRTDRWLVIDRKVYNITKWS IQHPGGQRVIGHYAGEDATDAFRAF HPDLEFVGKFLKPLLIGELAPEEPS QDHGKNSKITEDFRALRKTAEDMNL FKTNHVFFLLLLAHIIALESIAWFT VFYFGNGWIPTLITAFVLATSQAQA GWLQHDYGHLSVYRKPKWNHLVHKF VIGHLKGASANWWNHRHFQHHAKPN IFHKDPDVNMLHVFVLGEWQPIEYG KKKLKYLPYNHQHEYFFLIGPPLLI PMYFQYQIIMTMIVHKNWVDLAWAV SYYIRFFITYIPFYGILGALLFLNF IRFLESHWFVWVTQMNHIVMEIDQE AYRDWFSSQLTATCNVEQSFFNDWF SGHLNFQIEHHLFPTMPRHNLHKIA PLVKSLCAKHGIEYQEKPLLRALLD IIRSLKKSGKLWLDAYLHK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FADS2 fatty acid desaturase 2 [ Homo sapiens ]
• Official Symbol: FADS2
• Synonyms: FADS2; fatty acid desaturase 2; LLCDL2; D6D; delta 6 desaturase; DES6; FADSD6; SLL0262; TU13; delta-6 desaturase; delta-6-desaturase; delta(6) desaturase; delta-6 fatty acid desaturase; delta(6) fatty acid desaturase; linoleoyl-CoA desaturase (delta-6-desaturase)-like 2
• Gene ID: 9415
• mRNA Refseq: NM_004265
• Protein Refseq: NP_004256
• MIM: 606149
• UniProt ID: O95864