Recombinant Human FAH, MYC/DDK-tagged

• Cat.No.: FAH-87H
• Product Overview: Recombinant Human FAH, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT).
• Molecular Mass: 46.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) [ Homo sapiens (human) ]
• Official Symbol: FAH
• Synonyms: FAH; fumarylacetoacetate hydrolase (fumarylacetoacetase); fumarylacetoacetase; FAA; beta-diketonase; FLJ51912
• Gene ID: 2184
• mRNA Refseq: NM_000137
• Protein Refseq: NP_000128
• MIM: 613871
• UniProt ID: P16930
• Chromosome Location: 15q25.1
• Pathway: Metabolism of amino acids and derivatives; Phenylalanine and tyrosine catabolism; Tyrosine degradation, tyrosine => homogentisate
• Function: fumarylacetoacetase activity; metal ion binding