| Description : |
May participate in mRNA transport in the cytoplasm. Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
121.9 kDa |
| AA Sequence : |
MGVQGFQDYIEKHCPSAVVPVELQK LARGSLVGGGRQRPPQTPLRLLVDA DNCLHRLYGGFYTDWVSGGQWNHML GYLAALAKACFGGNIELFVFFNGAL EKARLHEWVKRQGNERQTAQQIVSH VQNKGTPPPKVWFLPPVCMAHCIRL ALIRFHVKVAQSIEDHHQEVIGFCR ENGFHGLVAYDSDYALCNIPYYFSA HALKLSRNGKSLTTSQYLMHEVAKQ LDLNPNRFPIFAALLGNHILPDEDL ASFHWSLLGPEHPLASLKVRAHQLV LPPCDVVIKAVADYVRNIQDTSDLD AIAKDVFQHSQSRTDDKVIRFKRAI GYYSATSKPMSFHPPHYLAARPGPF GMPGMVPPHVPPQMLNIPQTSLQAK PVAPQVPSPGGAPGQGPYPYSLSEP APLTLDTSGKNLTEQNSYSNIPHEG KHTPLYERSSPINPAQSGSPNHVDS AYFPGSSTSSSSDNDEGSGGATNHI SGNKIGWEKTGSHSEPQARGDPGDQ TKAEGSSTASSGSQLAEGKGSQMGT VQPIPCLLSMPTRNHMDITTPPLPP VAPEVLRVAEHRHKKGLMYPYIFHV LTKGEIKIAVSIEDEANKDLPPAAL LYRPVRQYVYGVLFSLAESRKKTER LAFRKNRLPPEFSPVIIKEWAAYKG KSPQTPELVEALAFREWTCPNLKRL WLGKAVEDKNRRMRAFLACMRSDTP AMLNPANVPTHLMVLCCVLRYMVQW PGARILRRQELDAFLAQALSPKLYE PDQLQELKIENLDPRGIQLSALFMS GVDMALFANDACGQPIPWEHCCPWM YFDGKLFQSKLLKASREKTPLIDLC DGQADQAAKVEKMRQSVLEGLSFSR QSHTLPFPPPPALPFYPASAYPRHF GPVPPSQGRGRGFAGVCGFGGPYGE TVATGPYRAFRVAAASGHCGAFSGS DSSRTSKSQGGVQPIPSQGGKLEIA GTVVGHWAGSRRGRGGRGPFPLQVV SVGGPARGRPRGVISTPVIRTFGRG GRYYGRGYKNQAAIQGRPPYAASAE EVAKELKSKSGESKSSAMSSDGSLA ENGVMAEEKPAPQMNGSTGDARAPS HSESALNNDSKTCNTNPHLNALSTD SACRREAALEAAVLNKEETRTRPLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
