| Description : |
This gene encodes a protein containing a FERM (4.2, exrin, radixin, moesin) domain, a Dbl homology domain, and two pleckstrin homology domains. These domains are found in guanine nucleotide exchange factors and proteins that link the cytoskeleton to the cell membrane. The encoded protein functions in neurons to promote dendritic growth. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
118.5 kDa |
| AA Sequence : |
MGEIEQRPTPGSRLGAPENSGISTL ERGQKPPPTPSGKLVSIKIQMLDDT QEAFEVPQRAPGKVLLDAVCNHLNL VEGDYFGLEFPDHKKITVWLDLLKP IVKQIRRPKHVVVKFVVKFFPPDHT QLQEELTRYLFALQVKQDLAQGRLT CNDTSAALLISHIVQSEIGDFDEAL DREHLAKNKYIPQQDALEDKIVEFH HNHIGQTPAESDFQLLEIARRLEMY GIRLHPAKDREGTKINLAVANTGIL VFQGFTKINAFNWAKVRKLSFKRKR FLIKLRPDANSAYQDTLEFLMASRD FCKSFWKICVEHHAFFRLFEEPKPK PKPVLFSRGSSFRFSGRTQKQVLDY VKEGGHKKVQFERKHSKIHSIRSLA SQPTELNSEVLEQSQQSTSLTFGEG AESPGGQSCRRGKEPKVSAGEPGSH PSPAPRRSPAGNKQADGAASAPTEE EEEVVKDRTQQSKPQPPQPSTGSLT GSPHLSELSVNSQGGVAPANVTLSP NLSPDTKQASPLISPLLNDQACPRT DDEDEGRRKRFPTDKAYFIAKEVST TERTYLKDLEVITSWFQSTVSKEDA MPEALKSLIFPNFEPLHKFHTNFLK EIEQRLALWEGRSNAQIRDYQRIGD VMLKNIQGMKHLAAHLWKHSEALEA LENGIKSSRRLENFCRDFELQKVCY LPLNTFLLRPLHRLMHYKQVLERLC KHHPPSHADFRDCRAALAEITEMVA QLHGTMIKMENFQKLHELKKDLIGI DNLVVPGREFIRLGSLSKLSGKGLQ QRMFFLFNDVLLYTSRGLTASNQFK VHGQLPLYGMTIEESEDEWGVPHCL TLRGQRQSIIVAASSRSEMEKWVED IQMAIDLAEKSSSPAPEFLASSPPD NKSPDEATAADQESEDDLSASRTSL ERQAPHRGNTMVHVCWHRNTSVSMV DFSIAVENQLSGNLLRKFKNSNGWQ KLWVVFTNFCLFFYKSHQDNHPLAS LPLLGYSLTIPSESENIQKDYVFKL HFKSHVYYFRAESEYTFERWMEVIR SATSSASRPHVLSHKESLVYTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
