Recombinant Human Fatty Acid Bbinding Protein 5
Cat.No. : | FABP5-527H |
Product Overview : | Recombinant human FABP5 was expressed inE.coliand purified by conventional chromatography. MW =15kDa (135aa). |
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- Gene Information
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Cat. No. : | FABP5-527H |
Description : | FABP5 is a member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to specifically bind fatty acids (FAs) with high affinity for stearic and linoleic acids. FABP5 is expressed in endothelial cells of the microvasculature of the placenta, heart, skeletal muscle, small intestine, lung, and renal medulla. FABP4 and FABP5 are closely related and both are expressed in adipocytes. Absence of FABP5 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. |
Source : | E.coli. |
Amino Acid Sequence : | MATVQQLEGR WRLVDSKGFD EYMKELGVGI ALRKMGAMAK PDCIITCDGKNLTIKTESTL KTTQFSCTLG EKFEETTADG RKTQTVCNFT DGALVQHQEWDGKESTI TRK LKDGKLVVEC VMNNVTCTRI YEKVE. |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 10% glycerol. |
Purity : | > 90% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | FABP5 fatty acid binding protein 5 (psoriasis-associated) [ Homo sapiens ] |
Synonyms : | FABP5; fatty acid binding protein 5 (psoriasis-associated); EFABP; E-FABP; PAFABP; PA-FABP; fatty acid binding protein 5 (psoriasis-associated); Psoriasis-associated fatty acid-binding protein homolog; Fatty acid-binding protein 5 |
Gene ID : | 2171 |
mRNA Refseq : | NM_001444 |
Protein Refseq : | NP_001435 |
MIM : | 605168 |
UniProt ID : | Q01469 |
Chromosome Location : | 8q21.13 |
Pathway : | AR signaling pathway |
Function : | ty acid binding; protein binding; transporter activity |
Products Types
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FABP5-3636H | Recombinant Human FABP5 Protein, GST-tagged | +Inquiry |
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Fabp5-1273M | Recombinant Mouse Fabp5 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
FABP5-6476HCL | Recombinant Human FABP5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionDysregulation or abnormal expression of FABP5 is associated with conditions such as cancer, metabolic disorders, and inflammatory diseases.
Fatty Acid-Binding Protein 5 (FABP5) functions in cellular processes, primarily playing a role in lipid metabolism and fatty acid transport.
FABP5 contributes to the regulation of lipid homeostasis and inflammatory responses in cells, linking lipid metabolism to immune function.
There are potential therapeutic implications related to FABP5 in diseases involving lipid metabolism and inflammation, making it a target for drug development.
FABP5 participates in the binding and transport of fatty acids within cells, facilitating their intracellular trafficking.
FABP5 is predominantly localized in the cytoplasm of cells, where it binds and transports fatty acids.
FABP5 preferentially interacts with long-chain fatty acids, influencing its cellular functions related to lipid metabolism.
Customer Reviews (3)
Write a reviewThe product's rapid action in triggering cellular responses significantly expedited our experiments.
Precise immunoprecipitation results consistently reflected the product's quality.
Replicating outcomes across diverse cell lines underscored the product's consistent behavior.
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