Recombinant Human FBLIM1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FBLIM1-2538H
• Product Overview: FBLIM1 MS Standard C13 and N15-labeled recombinant protein (NP_060026) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 40.7 kDa
• AA Sequence: MASKPEKRVASSVFITLAPPRRDVA VAEEVRQAVCEARRGRPWEAPAPMK TPEAGLAGRPSPWTTPGRAAATVPA APMQLFNGGCPPPPPVLDGEDVLPD LDLLPPPPPPPPVLLPSEEEAPAPM GASLIADLEQLHLSPPPPPPQAPAE GPSVQPGPLRPMEEELPPPPAEPVE KGASTDICAFCHKTVFPRELAVEAM KRQYHAQCFTCRTCRRQLAGQSFYQ KDGRPLCEPCYQDTLERCGKCGEVV RDHIIRALGQAFHPSCFTCVTCARC IGDESFALGSQNEVYCLDDFYRKFA PVCSICENPIIPRDGKDAFKIECMG RNFHENCYRCEDCRILLSVEPTDQG CYPLNNHLFCKPCHVKRSAAGCCTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FBLIM1 filamin binding LIM protein 1 [ Homo sapiens (human) ]
• Official Symbol: FBLIM1
• Synonyms: FBLIM1; filamin binding LIM protein 1; filamin-binding LIM protein 1; CAL; FBLP 1; migfilin; CSX-associated LIM; MIG2-interacting protein; filamin-binding LIM protein-1; mitogen-inducible 2 interacting protein; mitogen-inducible 2-interacting protein; FBLP1; FBLP-1; RP11-169K16.5; DKFZp434G171
• Gene ID: 54751
• mRNA Refseq: NM_017556
• Protein Refseq: NP_060026
• MIM: 607747
• UniProt ID: Q8WUP2