Recombinant Human FBLIM1 Protein, GST-tagged

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Recombinant Human FBLIM1 Protein, GST-tagged

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Cat.No. : FBLIM1-3870H
Product Overview : Human FBLIM1 full-length ORF (BAB55115.1, 1 a.a. - 276 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 57.2 kDa
AA Sequence : MASKPEKRVA SSVFITLAPP RRDVAVAEEV RQAVCEARRG RPWEAPAPMK TPEAGLAGRP SPWTTPGRAA ATVPAAPMQL FNGDICAFYH KTVFPRELAV EAMKRQYHAQ CFTCRTCRRQ LAGQSFYQKD GRPLCEPCYQ DTLERCGKCG EVVRDHIIRA LGQAFHPSCF TCVTCARCIG DESFALGSQN EVYCLDDFYR KFAPVCSICE NPIIPRDGKD AFKIECMGRN FHENCYRCED CRILLSVEPT DQGCYPLNNH LFCKPCHVKR SAAGCC
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : FBLIM1 filamin binding LIM protein 1 [ Homo sapiens ]
Official Symbol : FBLIM1
Synonyms : FBLIM1; filamin binding LIM protein 1; filamin-binding LIM protein 1; CAL; FBLP 1; migfilin; CSX-associated LIM; MIG2-interacting protein; filamin-binding LIM protein-1; mitogen-inducible 2 interacting protein; mitogen-inducible 2-interacting protein; FBLP1; FBLP-1; RP11-169K16.5; DKFZp434G171;
Gene ID : 54751
mRNA Refseq : NM_001024215
Protein Refseq : NP_001019386
MIM : 607747
UniProt ID : Q8WUP2

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