Recombinant Human FBN2 protein, His-tagged

• Cat.No.: FBN2-12H
• Product Overview: Recombinant Human FBN2(Thr1550~Cys1791) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a component of connective tissue microfibrils and may be involved in elastic fiber assembly. Mutations in this gene cause congenital contractural arachnodactyly.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 58.5kDa
• Protein length: Thr1550~Cys1791
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: FBN2 fibrillin 2 [ Homo sapiens ]
• Official Symbol: FBN2
• Synonyms: FBN2; fibrillin 2; CCA, congenital contractural arachnodactyly; fibrillin-2; DA9; fibrillin 5; CCA
• Gene ID: 2201
• mRNA Refseq: NM_001999
• Protein Refseq: NP_001990
• MIM: 612570
• UniProt ID: P35556
• Chromosome Location: 5q23-q31
• Function: binding; calcium ion binding; extracellular matrix structural constituent