Recombinant Human FBXL21 Protein, GST-tagged

• Cat.No.: FBXL21-3900H
• Product Overview: Human FBXL21 full-length ORF ( AAH44938.1, 1 a.a. - 70 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 6 tandem leucine-rich repeats. The amino acid sequence of this protein is highly similar to that of f-box and leucine-rich repeat protein 3A. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the non-coding allele. [provided by RefSeq, Jul 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 34.1 kDa
• AA Sequence: MNVSESHFVSALTVFINSKSLSSIK IEDTPVDDPSLKILVANNSDTLRLL KMSSCPHVSSDDGLHFLKLE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FBXL21 F-box and leucine-rich repeat protein 21 (gene/pseudogene) [ Homo sapiens ]
• Official Symbol: FBXL21
• Synonyms: FBXL21; F-box and leucine-rich repeat protein 21 (gene/pseudogene); F box and leucine rich repeat protein 3 pseudogene , F box and leucine rich repeat protein 21 , FBXL3B, FBXL3P; F-box/LRR-repeat protein 21; F box and leucine rich repeat protein 3B; FBL3B; Fbl21; F-box protein Fbl3b; F-box/LRR-repeat protein 3B; F-box and leucine-rich repeat protein 3B; F-box and leucine-rich repeat protein 3 pseudogene; FBXL3B; FBXL3P; MGC120237
• Gene ID: 26223
• mRNA Refseq: NM_012159
• Protein Refseq: NP_036291
• MIM: 609087
• UniProt ID: Q9UKT6