Recombinant Human FBXL5 Protein, GST-tagged

• Cat.No.: FBXL5-3907H
• Product Overview: Human FBXL5 full-length ORF ( AAH30656.1, 1 a.a. - 691 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 105 kDa
• AA Sequence: MAPFPEEVDVFTAPHWRMKQLVGLY CDKLSKTNFSNNNDFRALLQSLYAT FTEFKMHEQIENEYIIGLLQQRSQT IYNVHSDNKLSEMLSLFEKGLKNVK NEYEQLNYAKQLKERLEAFTRDFLP HMKEEEEVFQPMLMEYFTYEELKDI KKKVIAQHCSQKDTAELLRGLSLWN HAEERQKFFKYSVDEKSDKEAEVSE HSTGITHLPPEVMLSIFSYLNPQEL CRCSQVSMKWSQLTKTRSLWKHLYP VHWARGDWYSGPATELDTEPDDEWV KNRKDESRAFHEWDEDADIDESEES AEESIAISIAQMEKRLLHGLIHNVL PYVGTSVKTLVLAYSSAVSSKMVRQ ILELCPNLEHLDLTQTDISDSAFDS WSWLGCCQSLRHLDLSGCEKITDVA LEKISRALGILTSHQSGFLKTSTSK ITSTAWKNKDITMQSTKQYACLHDL TNKGIGEEIDNEHPWTKPVSSENFT SPYVWMLDAEDLADIEDTVEWRHRN VESLCVMETASNFSCSTSGCFSKDI VGLRTSVCWQQHCASPAFAYCGHSF CCTGTALRTMSSLPESSAMCRKAAR TRLPRGKDLIYFGSEKSDQETGRVL LFLSLSGCYQITDHGLRVLTLGGGL PYLEHLNLSGCLTITGAGLQDLVSA CPSLNDEYFYYCDNINGPHADTASG CQNLQCGFRACCRSGE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FBXL5 F-box and leucine-rich repeat protein 5 [ Homo sapiens ]
• Official Symbol: FBXL5
• Synonyms: FBXL5; F-box and leucine-rich repeat protein 5; F-box/LRR-repeat protein 5; FBL4; FBL5; FLR1; F-box protein FBL5; p45SKP2-like protein; F-box protein FBL4/FBL5
• Gene ID: 26234
• mRNA Refseq: NM_001193534
• Protein Refseq: NP_001180463
• MIM: 605655
• UniProt ID: Q9UKA1