| Description : |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
44.1 kDa |
| AA Sequence : |
MAGSEPRSGTNSPPPPFSDWGRLEA AILSGWKTFWQSVSKERVARTTSRE EVDEAASTLTRLPIDVQLYILSFLS PHDLCQLGSTNHYWNETVRDPILWR YFLLRDLPSWSSVDWKSLPDLEILK KPISEVTDGAFFDYMAVYRMCCPYT RRASKSSRPMYGAVTSFLHSLIIQN EPRFAMFGPGLEELNTSLVLSLMSS EELCPTAGLPQRQIDGIGSGVNFQL NNQHKFNILILYSTTRKERDRAREE HTSAVNKMFSRHNEGDDQQGSRYSV IPQIQKVCEVVDGFIYVANAEAHKR HEWQDEFSHIMAMTDPAFGSSGRPL LVLSCISQGDVKRMPCFYLAHELHL NLLNHPWLVQDTEAETLTGFLNGIE WILEEVESKRARSGPTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
