Recombinant Human FCGR3A protein(R167) , His-Avi-tagged
Cat.No. : | FCGR3A-142H |
Product Overview : | Recombinant Human Fc gamma RIIA/CD32a (R167) Protein is expressed from mammalian with a His and Avi tag at the C-terminal. It contains Ala 36 - Ile 218. |
- Specification
- Gene Information
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Description : | The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. The CD64 proteins are high affinity receptors (~10e-8-10e-9 M) capable of binding monomeric IgG, whereas the CD16 and CD32 proteins bind IgG with lower affinities (~10e-6-10e-7 M) only recognizing IgG aggregates surrounding multivalent antigens. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Molecular Mass : | The Protein has a calculated MW of 23.2kDa .As a result of glycosylation, the protein migrates as 34-40kDa based on Bis-Tris PAGE. |
Protein length : | It contains Ala 36 - Ile 218 . |
Endotoxin : | Less than 0.01EU per ug by the LAL method. |
Purity : | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) [ Homo sapiens ] |
Official Symbol : | FCGR3A |
Synonyms : | CD32 antigen; CD32a; CD32MGC23887; CDw32fc-gamma-RIIa; Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc gamma RIIA; FCG2; Fc-gamma RII-a; Fc-gamma-RIIa; FcGR; FCGR2; FCGR2A; FCGR2A1; FcgRIIA; FCRIIA; fcRII-a; IGFR2MGC30032; IgG Fc receptor II-a; Immunoglobulin G Fc receptor II; low affinity immunoglobulin gamma Fc region receptor II-a |
Gene ID : | 2214 |
mRNA Refseq : | NM_000569 |
Protein Refseq : | NP_000560 |
MIM : | 146740 |
UniProt ID : | P08637 |
Products Types
◆ Recombinant Protein | ||
FCGR3A-100H | Active Recombinant Human FCGR3A protein(Met1-Gln208,176F), His-Avi-tagged | +Inquiry |
FCGR3A-546H | Recombinant Human FCGR3A Protein (F176) | +Inquiry |
FCGR3A-3996H | Recombinant Human FCGR3A Protein, GST-tagged | +Inquiry |
FCGR3A-901H | Recombinant Human FCGR3A Protein, His (Fc)-Avi-tagged | +Inquiry |
FCGR3A-3995H | Recombinant Human FCGR3A Protein | +Inquiry |
◆ Lysates | ||
FCGR3A-1999HCL | Recombinant Human FCGR3A cell lysate | +Inquiry |
FCGR3A-1969RCL | Recombinant Rat FCGR3A cell lysate | +Inquiry |
FCGR3A-001HCL | Recombinant Human FCGR3A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionFCGR3A activates immune cells and mediates phagocytosis, aiding in the clearance of pathogens and antibody-coated targets.
FCGR3A is key in antibody-dependent cellular cytotoxicity, crucial for the effectiveness of certain cancer immunotherapies.
Genetic variations in FCGR3A influence responses to monoclonal antibody treatments, affecting treatment efficacy.
FCGR3A helps regulate the immune system's balance between activation and tolerance, preventing overactive immune responses.
Changes in FCGR3A function or expression can influence vaccine efficacy, impacting immune system responses to vaccination.
FCGR3A plays a role in the inflammatory response to infections, contributing to pathogen clearance and immune regulation.
FCGR3A expression impacts the development and severity of autoimmune diseases by modulating immune responses.
Customer Reviews (3)
Write a reviewOutstanding protein-protein interaction studies, boosts our experiments.
Swift protein quantification, improves data reliability.
Expertise in peptide synthesis, accelerates our peptide-based projects.
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