Recombinant Human FCGRT protein, His & T7-tagged

• Cat.No.: FCGRT-1629H
• Product Overview: Recombinant Human FCGRT aa. (Ala24~Ala365 (Accession # P55899)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 41.0kDa
• Protein length: Ala24~Ala365 (Accession # P55899)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 5.9

Gene Information

• Gene Name: FCGRT Fc fragment of IgG receptor and transporter [ Homo sapiens (human) ]
• Official Symbol: FCGRT
• Synonyms: FCGRT; Fc fragment of IgG receptor and transporter; FCRN; alpha-chain; IgG receptor FcRn large subunit p51; Fc fragment of IgG, receptor, transporter, alpha; FcRn alpha chain; IgG Fc fragment receptor transporter alpha chain; heavy chain of the major histocompatibility complex class I-like Fc receptor; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; neonatal Fc receptor; neonatal Fc-receptor for Ig; transmembrane alpha chain of the neonatal receptor
• Gene ID: 2217
• mRNA Refseq: NM_001136019.2
• Protein Refseq: NP_001129491.1
• UniProt ID: P55899