Recombinant Human FCN1 Protein (Ala30-Ala326), His tagged

• Cat.No.: FCN1-3016H
• Product Overview: Recombinant human FCN1 (Ala30-Ala326) protein fused with His tag was expressed in E. coli.

Specification

• Description: Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 33.67 kDa
• Protein Length: Ala30-Ala326
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: FCN1 ficolin (collagen/fibrinogen domain containing) 1 [ Homo sapiens (human) ]
• Official Symbol: FCN1
• Synonyms: FCN1; ficolin (collagen/fibrinogen domain containing) 1; ficolin-1; FCNM; M-ficolin; ficolin-A; ficolin-alpha; collagen/fibrinogen domain-containing protein 1; ficolin (collagen/fibrinogen domain-containing) 1
• Gene ID: 2219
• mRNA Refseq: NM_002003
• Protein Refseq: NP_001994
• MIM: 601252
• UniProt ID: O00602