Recombinant Human Feline Sarcoma Oncogene, GST-tagged, Active

• Cat.No.: FES-311H
• Product Overview: Recombinant full-length human FES was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=125kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: FES is a protooncogene that encodes a protein-tyrosine kinase distinct from c-Src, c-Abl and other nonreceptor tyrosine kinases. FES was originally identified as the cellular homolog of several transforming retroviral oncoproteins. FES plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell-cell interaction.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70^oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: FES feline sarcoma oncogene [ Homo sapiens ]
• Synonyms: FES; feline sarcoma oncogene; FPS; c-fes/fps protein; Oncogene FES, feline sarcoma virus; proto-oncogene tyrosine-protein kinase Fes/Fps; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog; EC 2.7.10.2
• Gene ID: 2242
• mRNA Refseq: NM_001143783
• Protein Refseq: NP_001137255
• MIM: 190030
• UniProt ID: P07332
• Chromosome Location: 15q26
• Pathway: Axon guidance
• Function: ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; receptor activity; transferase activity