Recombinant Human FEV Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FEV-1543H
• Product Overview: FEV MS Standard C13 and N15-labeled recombinant protein (NP_059991) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 24.8 kDa
• AA Sequence: MRQSGASQPLLINMYLPDPVGDGLF KDGKNPSWGPLSPAVQKGSGQIQLW QFLLELLADRANAGCIAWEGGHGEF KLTDPDEVARRWGERKSKPNMNYDK LSRALRYYYDKNIMSKVHGKRYAYR FDFQGLAQACQPPPAHAHAAAAAAA AAAAAQDGALYKLPAGLAPLPFPGL SKLNLMAASAGVAPAGFSYWPGPGP AATAAAATAALYPSPSLQPPPGPFG AVAAASHLGGHYHTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FEV FEV transcription factor, ETS family member [ Homo sapiens (human) ]
• Official Symbol: FEV
• Synonyms: FEV; FEV transcription factor, ETS family member; PET-1; HSRNAFEV; protein FEV; FEV (ETS oncogene family); FEV, ETS transcription factor; PC12 ETS domain-containing transcription factor 1; fifth Ewing variant protein
• Gene ID: 54738
• mRNA Refseq: NM_017521
• Protein Refseq: NP_059991
• MIM: 607150
• UniProt ID: Q99581