Recombinant Human FEZ1, GST-tagged

• Cat.No.: FEZ1-12849H
• Product Overview: Recombinant Human FEZ1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-321a.a.
• Description: This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FEZ1 fasciculation and elongation protein zeta 1 (zygin I) [ Homo sapiens ]
• Official Symbol: FEZ1
• Synonyms: FEZ1; fasciculation and elongation protein zeta 1 (zygin I); fasciculation and elongation protein zeta-1; zygin I; zygin-1
• Gene ID: 9638
• mRNA Refseq: NM_005103
• Protein Refseq: NP_005094
• MIM: 604825
• UniProt ID: Q99689
• Chromosome Location: 11q24.2
• Function: gamma-tubulin binding; protein binding; protein kinase C binding