Recombinant Human FGF21, Fc-tagged

• Cat.No.: FGF21-28829TH
• Product Overview: Recombinant full length Human FGF21 fused at the C terminus to the Fc portion of Human IgG1; MWt 50 kDa by SDS Page.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 209 amino acids
• Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.
• Conjugation: Fc
• Molecular Weight: 50.000kDa inclusive of tags
• Biological activity: Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: PBS
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the heparin-binding growth factors family.

Gene Information

• Gene Name: FGF21 fibroblast growth factor 21 [ Homo sapiens ]
• Official Symbol: FGF21
• Synonyms: FGF21; fibroblast growth factor 21
• Gene ID: 26291
• mRNA Refseq: NM_019113
• Protein Refseq: NP_061986
• MIM: 609436
• Uniprot ID: Q9NSA1
• Chromosome Location: 19q13.1-qter
• Pathway: MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Melanoma, organism-specific biosystem; Melanoma, conserved biosystem; Pathways in cancer, organism-specific biosystem
• Function: growth factor activity; protein binding