Recombinant Human FGF21, Fc-tagged FGF21-28829TH

Recombinant Human FGF21, Fc-tagged

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Cat.No. : FGF21-28829TH Optional Service: Optional requirements on this protein
Product Overview : Recombinant full length Human FGF21 fused at the C terminus to the Fc portion of Human IgG1; MWt 50 kDa by SDS Page.
Description : The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.
Protein length : 209 amino acids
Conjugation : Fc
Molecular Weight : 50.000kDa inclusive of tags
Source : HEK 293 cells
Biological activity : Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: PBS
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the heparin-binding growth factors family.
Gene Name : FGF21 fibroblast growth factor 21 [ Homo sapiens ]
Official Symbol : FGF21
Synonyms : FGF21; fibroblast growth factor 21;
Gene ID : 26291
mRNA Refseq : NM_019113
Protein Refseq : NP_061986
MIM : 609436
Uniprot ID : Q9NSA1
Chromosome Location : 19q13.1-qter
Pathway : MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Melanoma, organism-specific biosystem; Melanoma, conserved biosystem; Pathways in cancer, organism-specific biosystem;
Function : growth factor activity; protein binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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