Recombinant Human FGFR1 protein, His-Avi-tagged
Cat.No. : | FGFR1-362H |
Product Overview : | Human FGFR1 alpha (IIIc) Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains Arg22-Glu374. |
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- Gene Information
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Description : | Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding.FGFR1 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Molecular Mass : | The protein has a predicted MW of 42 KDa. Due to glycosylation, the protein migrates to 68-80 KDa based on Bis-Tris PAGE result. |
Protein length : | Arg22-Glu374 |
Endotoxin : | Less than 0.05 EU per ug by the LAL method. |
Purity : | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Gene Name : | FGFR1 fibroblast growth factor receptor 1 [ Homo sapiens (human) ] |
Official Symbol : | FGFR1 |
Synonyms : | FGF R1a; FGFR1 alpha |
Gene ID : | 2260 |
mRNA Refseq : | NM_001174063.2 |
Protein Refseq : | NP_001167534.1 |
MIM : | 136350 |
UniProt ID : | P11362 |
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◆ Lysates | ||
FGFR1-476HCL | Recombinant Human FGFR1 cell lysate | +Inquiry |
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◆ Assay kits | ||
Kit-1557 | U2OS FGFR1 Bioassay Kit | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDEFB103A plays a role in maintaining a balanced microbiome by exerting selective antimicrobial activity. Understanding this interaction is crucial for potential applications in microbiome-related disorders.
Research suggests that altered levels of DEFB103A expression may be associated with certain diseases. However, its specific use as a diagnostic marker requires further validation.
While research is ongoing, potential side effects and concerns related to the therapeutic use of DEFB103A or its analogs need to be thoroughly investigated, including any possible immunogenicity.
DEFB103A plays a crucial role in the innate immune system by acting as an antimicrobial peptide. It helps defend the body against a wide range of pathogens, including bacteria, viruses, and fungi.
DEFB103A deficiency has been linked to an increased susceptibility to various infections, particularly those affecting the skin and mucosal surfaces.
Customer Reviews (3)
Write a reviewFGFR1, a calcium-dependent phospholipid-binding protein, plays a crucial role in various cellular processes, making it a valuable tool for investigation.
When combined with the support and quality assurance provided by the manufacturer, researchers can confidently utilize FGFR1 protein to unravel the intricate mechanisms underlying cellular processes, ultimately advancing scientific knowledge.
The manufacturer can contribute to the research process by providing top-quality FGFR1 protein that meets rigorous standards of purity, stability, and reliability.
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