Recombinant Human FGFR3 Protein, His-tagged
Cat.No. : | FGFR3-151H |
Product Overview : | Recombinant Human fibroblast growth factor receptor 3(FGFR3), transcript variant 2(NM_022965), with a His tag, was expressed in human cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. |
Source : | Human Cells |
Species : | Human |
Tag : | His |
Form : | Purified protein formulated in a sterile solution of TBS buffer, pH7.168, without any preservatives. |
Molecular Mass : | 34 kDa |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |
Gene Name : | FGFR3 fibroblast growth factor receptor 3 [ Homo sapiens ] |
Official Symbol : | FGFR3 |
Synonyms : | FGFR3; fibroblast growth factor receptor 3; ACH, achondroplasia, thanatophoric dwarfism; CD333; CEK2; JTK4; FGFR-3; tyrosine kinase JTK4; hydroxyaryl-protein kinase; ACH; HSFGFR3EX; |
Gene ID : | 2261 |
mRNA Refseq : | NM_000142 |
Protein Refseq : | NP_000133 |
MIM : | 134934 |
UniProt ID : | P22607 |
Products Types
◆ Recombinant Protein | ||
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FGFR3-93H | Recombinant Human FGFR3 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
Fgfr3-624M | Active Recombinant Mouse Fgfr3 protein(Met1-Tyr367), His-tagged | +Inquiry |
FGFR3-4136H | Active Recombinant Human FGFR3 Protein, GST-tagged | +Inquiry |
Fgfr3-10554M | Recombinant Mouse Fgfr3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FGFR3-2596MCL | Recombinant Mouse FGFR3 cell lysate | +Inquiry |
FGFR3-001CCL | Recombinant Cynomolgus FGFR3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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