Recombinant Human Fibroblast Growth Factor 9 (Glia-activating Factor)

Species :	Human
Source :	Sf21 Cells
Tag :	Non
Description :	Fibroblast growth factor 9 (glia-activating factor), also known as FGF9 is a glycosylated neurotrophic polypeptide highly expressed in brain. It is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development.
Molecular Weight :	The predicted molecular weight of Recombinant Human FGF-9 is Mr 23 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 25-27 kDa.
State Of Matter :	Lyophilized.
Purity :	>97% by SDS Page and analyzed by silver stain.
Endotoxin :	<1.0 EU/µg as determined by the LAL method.
Biological Activity :	The biological activity of Human FGF-9 was determined by its ability to stimulate proliferation of a mouse fibroblast cell line, Balb/3T3.
Storage And Stability :	This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer.

Gene Name	FGF9 fibroblast growth factor 9 (glia-activating factor) [ Homo sapiens ]
Synonyms	FGF9; fibroblast growth factor 9 (glia-activating factor); GAF; SYNS3; HBFG-9; MGC119914; MGC119915; fibroblast growth factor 9; glia-activating factor; FGF-9; HBGF-9; MGC119914; OTTHUMP00000018804
Gene ID	2254
mRNA Refseq	NM_002010
Protein Refseq	NP_002001
MIM	600921
UniProt ID	P31371
Chromosome Location	13q11-q12
Pathway	MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of actin cytoskeleton; Signaling by FGFR
Function	fibroblast growth factor receptor binding; growth factor activity; heparin binding