Recombinant Human Fibroblast Growth Factor 9 (Glia-activating Factor)

Cat.No. : FGF9-336H
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Cat. No. : FGF9-336H
Description : Fibroblast growth factor 9 (glia-activating factor), also known as FGF9 is a glycosylated neurotrophic polypeptide highly expressed in brain. It is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development.
Source : Sf21 Insect Cells.
Molecular Weight : The predicted molecular weight of Recombinant Human FGF-9 is Mr 23 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 25-27 kDa.
State Of Matter : Lyophilized.
Purity : >97% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Biological Activity : The biological activity of Human FGF-9 was determined by its ability to stimulate proliferation of a mouse fibroblast cell line, Balb/3T3.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer.
Tag : Non
Gene Name : FGF9 fibroblast growth factor 9 (glia-activating factor) [ Homo sapiens ]
Synonyms : FGF9; fibroblast growth factor 9 (glia-activating factor); GAF; SYNS3; HBFG-9; MGC119914; MGC119915; fibroblast growth factor 9; glia-activating factor; FGF-9; HBGF-9; MGC119914; OTTHUMP00000018804
Gene ID : 2254
mRNA Refseq : NM_002010
Protein Refseq : NP_002001
MIM : 600921
UniProt ID : P31371
Chromosome Location : 13q11-q12
Pathway : MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of actin cytoskeleton; Signaling by FGFR
Function : fibroblast growth factor receptor binding; growth factor activity; heparin binding

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