Recombinant Human Fibroblast Growth Factor Receptor 1, His-tagged
Cat.No. : | FGFR1-5417H |
Product Overview : | Recombinant humanFGFR1 catalytic domain (amino acids 308-731), His-tagged. No special measureswere taken to activate this kinase. |
- Specification
- Gene Information
- Related Products
Cat. No. : | FGFR1-5417H |
Description : | FGFs comprise a family of atleast eighteen structurally realted proteins that are involved in a multitudeof physiological and pathological cellular processes, including cell growth,differentation, angiogenesis, wound healing and tumorgenesis. The biologicalactivities of the FGFs are mediated by a family if type I transmembranetyrosine kinases which undergo dimerization and autophosphorylation afterligand binding. |
Source : | Insect cells |
Species : | Human |
Form : | Liquid in50 mM Tris, pH 7.5 + 100 mM NaCl + 0.2 mM EDTA + 0.05% Triton X-100 + 5mM DTT+ 50% glycerol. |
Molecular Weight : | 50.4 kDa |
Purity : | ≥ 90% as determinedby SDS-PAGE analysis |
Specific Activity : | 620 nmoleof phosphate transferred to poly [Glu,Tyr] 4:1 substrate per minute per mg of totalprotein at 30°C. Activity determined at a final protein concentration of 2μg/ml. |
Storage : | Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | FGFR1 |
Gene Name : | FGFR1 fibroblast growth factorreceptor 1 [ Homo sapiens ] |
Synonyms : | FGFR1; fibroblast growth factorreceptor 1; CEK; FLG; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; HBGFR; N-SAM;FLJ99988; fms-related tyrosine kinase 2; H2; H3; H4; H5; N-SAM; CD331;Pfeiffer syndrome; FGFR-1; bFGF-R; EC 2.7.10.1; Fms-like tyrosine kinase 2;c-fgr; CD_antigen; OTTHUMP00000190881; soluble FGFR1 variant 1; FMS-liketyrosine kinase 2; hydroxyaryl-protein kinase; heparin-binding growth factorreceptor; basic fibroblast growth factor receptor 1; OTTHUMP00000190874;OTTHUMP00000190878; OTTHUMP00000190879; c-fgr; soluble FGFR1 variant 2 |
Gene ID : | 2260 |
mRNA Refseq : | NM_015850 |
Protein Refseq : | NP_056934 |
MIM : | 136350 |
UniProt ID : | P11362 |
Chromosome Location : | 8p11.2-p11.1 |
Pathway : | Adherens junction; Axonguidance; Developmental Biology; Downstream signaling of activated FGFR; EndochondralOssification; FGF signaling pathway; FGFR ligand binding and activation; FRS2-mediatedcascade; Glypican 1 network; IRS-mediated signalling; Insulin receptorsignalling cascade; L1CAM interactions; MAPK signaling pathway; Melanoma; N-cadherinsignaling events; Negative regulation of FGFR signaling |
Function : | ATP binding; fibroblast growthfactor receptor activity; fibroblast growth factor receptor activity; heparinbinding; nucleotide binding; protein binding; receptor activity; transferaseactivity |
Products Types
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FGFR1-4407H | Recombinant Human FGFR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FGFR1-91H | Recombinant Active Human FGFR1 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
FGFR1-2133MCL | Recombinant Mouse FGFR1 cell lysate | +Inquiry |
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◆ Assay kits | ||
Kit-1557 | U2OS FGFR1 Bioassay Kit | +Inquiry |
Kit-1590 | FGFR1 Functional Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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