Recombinant Human FKBP1B Protein

• Cat.No.: FKBP1B-001H
• Product Overview: Recombinant Human FKBP1B Protein (1-108 aa (full-length)) without tag (GST tag removed) was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: 1-108
• Description: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
• Molecular Mass: 12.05 kDa
• Purity: >95% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB).
• Applications: ELISA, Western Blot, Antibody Production, Protein array
• Quality Control Test: 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-GST serum (WB) and peptide fingerprinting by MALDI-TOF-TOF mass spectrometry.
• Storage: Prior to reconstitution, store the lyophilized protein at 2−8 centigrade. After reconstitution, store in working aliquots at −80 centigrade.
• Expiry: All components are stable for 1 year of receipt, if stored properly.
• Storage Buffer: Phosphate-Buffered Saline (PBS), pH 7.4. No preservatives added.
• Shipping: Lyophilized at Ambient temperature

Gene Information

• Gene Name: FKBP1B FKBP prolyl isomerase 1B [ Homo sapiens (human) ]
• Official Symbol: FKBP1B
• Synonyms: FKBP1B; FKBP prolyl isomerase 1B; OTK4; FKBP1L; PKBP1L; PPIase; FKBP12.6; peptidyl-prolyl cis-trans isomerase FKBP1B; 12.6 kDa FK506-binding protein; 12.6 kDa FKBP; FK506 binding protein 1B, 12.6 kDa; FK506-binding protein 12.6; FK506-binding protein 1B; FKBP-12.6; FKBP-1B; PPIase FKBP1B; calstabin 2; h-FKBP-12; immunophilin FKBP12.6; rotamase; EC 5.2.1.8
• Gene ID: 2281
• mRNA Refseq: NM_004116
• Protein Refseq: NP_004107
• MIM: 600620
• UniProt ID: P68106