Recombinant Human FLCN Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FLCN-3503H
• Product Overview: FLCN MS Standard C13 and N15-labeled recombinant protein (NP_659434) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 64.3 kDa
• AA Sequence: MNAIVALCHFCELHGPRTLFCTEVL HAPLPQGDGNEDSPGQGEQAEEEEG GIQMNSRMRAHSPAEGASVESSSPG PKKSDMCEGCRSLAAGHPGYISHDK ETSIKYVSHQHPSHPQLFSIVRQAC VRSLSCEVCPGREGPIFFGDEQHGF VFSHTFFIKDSLARGFQRWYSIITI MMDRIYLINSWPFLLGKVRGIIDEL QGKALKVFEAEQFGCPQRAQRMNTA FTPFLHQRNGNAARSLTSLTSDDNL WACLHTSFAWLLKACGSRLTEKLLE GAPTEDTLVQMEKLADLEEESESWD NSEAEEEEKAPVLPESTEGRELTQG PAESSSLSGCGSWQPRKLPVFKSLR HMRQVLGAPSFRMLAWHVLMGNQVI WKSRDVDLVQSAFEVLRTMLPVGCV RIIPYSSQYEEAYRCNFLGLSPHVQ IPPHVLSSEFAVIVEVHAAARSTLH PVGCEDDQSLSKYEFVVTSGSPVAA DRVGPTILNKIEAALTNQNLSVDVV DQCLVCLKEEWMNKVKVLFKFTKVD SRPKEDTQKLLSILGASEEDNVKLL KFWMTGLSKTYKSHLMSTVRSPTAS ESRNTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FLCN folliculin [ Homo sapiens (human) ]
• Official Symbol: FLCN
• Synonyms: FLCN; folliculin; BHD; MGC17998; MGC23445; birt-Hogg-Dube syndrome protein; BHD skin lesion fibrofolliculoma protein; FLCL; FLJ45004; FLJ99377; DKFZp547A118
• Gene ID: 201163
• mRNA Refseq: NM_144997
• Protein Refseq: NP_659434
• MIM: 607273
• UniProt ID: Q8NFG4