Recombinant Human FLI1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FLI1-758H
• Product Overview: FLI1 MS Standard C13 and N15-labeled recombinant protein (NP_002008) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51 kDa
• AA Sequence: MDGTIKEALSVVSDDQSLFDSAYGA AAHLPKADMTASGSPDYGQPHKINP LPPQQEWINQPVRVNVKREYDHMNG SRESPVDCSVSKCSKLVGGGESNPM NYNSYMDEKNGPPPPNMTTNERRVI VPADPTLWTQEHVRQWLEWAIKEYS LMEIDTSFFQNMDGKELCKMNKEDF LRATTLYNTEVLLSHLSYLRESSLL AYNTTSHTDQSSRLSVKEDPSYDSV RRGAWGNNMNSGLNKSPPLGGAQTI SKNTEQRPQPDPYQILGPTSSRLAN PGSGQIQLWQFLLELLSDSANASCI TWEGTNGEFKMTDPDEVARRWGERK SKPNMNYDKLSRALRYYYDKNIMTK VHGKRYAYKFDFHGIAQALQPHPTE SSMYKYPSDISYMPSYHAHQQKVNF VPPHPSSMPVTSSSFFGAASQYWTS PTGGIYPNPNVPRHPNTHVPSHLGS YYTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FLI1 Friend leukemia virus integration 1 [ Homo sapiens (human) ]
• Official Symbol: FLI1
• Synonyms: FLI1; Friend leukemia virus integration 1; Friend leukemia integration 1 transcription factor; EWSR2; SIC 1; proto-oncogene Fli-1; transcription factor ERGB; SIC-1
• Gene ID: 2313
• mRNA Refseq: NM_002017
• Protein Refseq: NP_002008
• MIM: 193067
• UniProt ID: Q01543