Cat.No. : |
FLRT2-2342H
Optional Service: Optional requirements on this protein
|
Product Overview : |
Recombinant human FLRT2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293 |
Description : |
This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
MYC/DDK |
Form : |
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : |
73.9 kDa |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : |
>50 ug/mL as determined by microplate BCA method |