Recombinant Human FLT3, GST-His
Cat.No. : | FLT3-688H |
Product Overview : | Recombinant human Flt-3 fused at the N-terminus to a GST-His6 thrombin cleavage site sequence was expressed inS. frugiperdainsect cells using a baculovirus expression system. MW = 82076 Da. |
- Specification
- Gene Information
- Related Products
Cat. No. : | FLT3-688H |
Description : | Flt-3 belongs to the class III receptor tyrosine kinase family that is closely related to c-Kit and c-Fms. It is expressed in primitive hematopoietic cells and its ligand exerts proliferative effects on these cells in vitro in cooperation with other cytokines. Flt-3 is also expressed in the placenta, testis, spleen, thymus, bone marrow, brain and in cerebellar Purkinje cells. |
Source : | S. frugiperda. |
Form : | Liquid. In 100 mM NaCl, 50 mM Tris-HCl, 15 mM reduced glutathione, 5 mM DTT, 20% glycerol, pH 8.0. Please refer to vial label for lot-specific concentration. |
Unit Definition : | One unit is defined as the amount of enzyme required to transfer 1 nmol phosphate to Poly(Glu,Tyr)4:1 per min at 30°C, using variable concentrations of ATP (0.1-12.6 µM). |
Specific Activity : | ≥28 U/mg protein. |
Toxicity : | Standard Handling (MSDS available upon request). |
Storage : | ≤ -70°C. Avoid freeze/thaw Following initial thaw, aliquot and freeze (-70°C). |
Gene Name : | FLT3 fms-related tyrosine kinase 3 [ Homo sapiens ] |
Synonyms : | FLT3; fms-related tyrosine kinase 3; FLK2; STK1; CD135; CD135 antigen; fetal liver kinase 2; FL cytokine receptor; tal liver kinase 2; stem cell tyrosine kinase 1; FLT3 receptor tyrosine kinase; tyrosine-protein kinase receptor FLT3; growth factor receptor tyrosine kinase type III; C 2.7.10.1; OTTHUMP00000042340; fetal liver kinase 2 |
Gene ID : | 2322 |
mRNA Refseq : | NM_004119 |
Protein Refseq : | NP_004110 |
MIM : | 136351 |
UniProt ID : | P36888 |
Chromosome Location : | 13q12 |
Pathway : | ute myeloid leukemia; Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Pathways in cancer |
Function : | ATP binding; nucleotide binding; osphoinositide 3-kinase binding; protein binding; receptor activity; transferase activity; vascular endothelial growth factor receptor activity |
Products Types
◆ Recombinant Protein | ||
FLT3-038H | Recombinant Human FLT3 Protein, C-His-tagged | +Inquiry |
FLT3-188H | Recombinant Human FLT3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Flt3-10555M | Recombinant Mouse Flt3 Protein, His (Fc)-Avi-tagged | +Inquiry |
FLT3-97P | Active Recombinant Porcine FLT-3 Ligand Protein | +Inquiry |
FLT3-4371H | Recombinant Human FLT3 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
FLT3-2561HCL | Recombinant Human FLT3 cell lysate | +Inquiry |
FLT3-970MCL | Recombinant Mouse FLT3 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1593 | Flt3 Activity Assay Kit | +Inquiry |
Kit-1592 | Flt3 ActivityAssay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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